A-SCAL Stem Cell Exo hair growth solution

A-SCAL stem cell exosome hair growth solution is a clinically formulated hair restoration solution designed to address the multifactorial causes of hair loss through a comprehensive, science-backed approach. At its core is stem cell, enriched with potent growth factors such as VEGF, HGF, TGF-β1, KGF, bFGF, and PDGF. These factors work synergistically to stimulate dermal papilla cell regeneration, enhance follicular vitality, and combat early-stage alopecia. Stem cell are known for their role in cell signaling and regeneration—are naturally present in the conditioned media, along with a variety of potent growth factors that support hair follicle regeneration and scalp health.

Three Factors that cause hair loss

1. Dihydrotestosterone (DHT)

DHT is a high-potency androgen (male hormone) that is a major contributor to androgenic alopecia. It is produced when testosterone is converted by the enzyme 5α-reductase. DHT binds to androgen receptors in hair follicles, leading to their miniaturization, which results in thinning and eventual hair loss.

2. 5α-Reductase

This enzyme is responsible for converting testosterone into DHT. Increased activity of 5α-reductase leads to higher levels of DHT, which negatively impacts hair growth by shrinking hair follicles over time.

3. Androgen Receptors

These receptors are proteins within hair follicle cells that bind and respond to DHT and testosterone. When DHT binds to these receptors in genetically susceptible individuals, it triggers follicular regression and hair loss.

A-SCAL Stem Cell hair growth solution targets these mechanisms by inhibiting DHT and supporting follicle regeneration.

The formulation also includes Copper Tripeptide-1, which significantly inhibits dihydrotestosterone (DHT), a key contributor to androgenic hair loss, while simultaneously improving microcirculation and promoting anti-inflammatory activity. Dexpanthenol, a pro-vitamin B5 derivative, helps regulate sebum production and create an optimal scalp environment for hair growth.

Complementary ingredients such as biotin, cysteine, methionine, and bioactive peptides (EGF, IGF, and sh-polypeptides) contribute to keratin synthesis, follicle strength, and prolonged anagen phase duration. Clinical and histological data demonstrate that A-SCAL enhances hair density, increases follicle size, and improves overall scalp health.

This hair restoration solution is administered either through Hydra Pen H3, or topical application with Tok Stick, offering effective management for both early and progressive hair thinning.

Primary Ingredients:

1. Stem Cell EXO
   – Rich in growth factors such as VEGF, HGF, TGF-β1, KGF, bFGF, and PDGF
   – Supports dermal papilla cell regeneration and hair follicle activation

2. Copper Tripeptide-1
   – Strongly inhibits DHT
   – Promotes hair growth, enhances follicle size, and improves blood circulation

3. Dexpanthenol (Vitamin B5 Derivative)
   – Enhances scalp health by reducing sebum production
   – Promotes collagen synthesis and scalp regeneration

Peptides / Growth Factors:

4. sh-Polypeptide-1 (EGF – Epidermal Growth Factor)
   – Stimulates cell division and collagen production
   – Promotes transition into anagen (growth) phase

5. sh-Oligopeptide-2 (IGF – Insulin-like Growth Factor)
   – Stimulates cell proliferation and nutrient delivery to follicles

6. sh-Polypeptide-9 (VEGF – Vascular Endothelial Growth Factor)
   – Promotes angiogenesis and nutrient circulation in the scalp

Key Amino Acids and Nutrients:

7. Cysteine
   – Essential for keratin formation
   – Improves strength and elasticity of hair

8. Methionine
   – Supports keratin and ceramide production
   – Helps protect and strengthen hair shafts

9. Biotin (Vitamin B7)
   – Enhances keratin synthesis
   – Improves blood circulation and nutrient absorption in scalp tissue

10. Free Amino Acids (unspecified blend)
    – Stimulate keratin production
    – Promote follicular activity and hair strength

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